Drone and missile strikes on Ukraine's capital killed at least two people as Russia targeted the country's energy infrastructure in a "massive" attack overnight, according to Ukrainian officials.

"The death toll in the capital has risen to two," Tymur Tkachenko said on Telegram on October 22, as other city officials reported a major drone attack on the city.

Ukraine's Energy Minister Svitlana Hrynchuk stated on Facebook that Russia had carried out a "massive" overnight attack targeting the country's energy infrastructure.

In a message posted on October 22, Kyiv Mayor Vitaliy Klitschko said that as a result of the Russian attack on the capital, two people were killed and five others were injured.

"Medical personnel hospitalized all the injured, including a two-year-old child," he added.

He said that debris from drones and missiles caused fires in Kyiv's Dnipro, Pechersk, and Darnytsya districts, damaging residential buildings and industrial sites.

The attack began late on October 21 as witnesses reported hearing explosions and air defense units in operation.

Emergency services were dispatched to several sites where debris from the destroyed air weapons fell, sparking fires.

A house caught fire in the region surrounding Kyiv, injuring an elderly woman, said regional Governor Mykola Kalashnyk on Telegram.

Authorities in southeastern Ukraine also reported attacks. Russian drones hit the city of Zaporizhzhya, igniting fires in several residential buildings, regional Governor Ivan Fedorov said on Telegram.